Biofilms are invisible architects of bacterial survival, shaping environments from the human body to industry. Understanding their mechanics is crucial for breakthroughs in medicine, biotechnology, and public health. This book delves into biofilm science within the context of biohybrid microswimmers, offering insights for professionals, students, and enthusiasts alike.
Chapters Brief Overview:
1: Biofilm — Examines biofilm formation, its role in microbial survival, and its impact on human health.
2: Niels Høiby — Highlights the pioneering work of Niels Høiby in chronic infections and biofilm research.
3: Filamentation — Explores bacterial filamentation and its significance in biofilm resilience and adaptation.
4: Extracellular polymeric substance — Investigates the protective matrix that strengthens biofilm communities.
5: Pseudomonas aeruginosa — Analyzes this notorious pathogen’s biofilm formation and antibiotic resistance.
6: Acinetobacter baumannii — Discusses its role in hospital infections and its biofilmmediated persistence.
7: Roberto Kolter — Showcases Roberto Kolter’s contributions to biofilm research and bacterial behavior.
8: Persister cells — Examines dormant bacterial cells that evade antibiotics and prolong infections.
9: Rhamnolipid — Explores biosurfactants in biofilm development and their industrial applications.
10: Diffusible signal factor — Investigates bacterial communication and its influence on biofilm dynamics.
11: Bacterial morphological plasticity — Analyzes shapeshifting bacteria adapting to hostile environments.
12: Antimicrobial peptides — Explores nature’s antibiotics and their potential against biofilmrelated infections.
13: Stenotrophomonas maltophilia — Discusses this emerging pathogen and its biofilmforming capabilities.
14: ESKAPE — Highlights multidrugresistant pathogens that thrive within biofilms.
15: Drug resistance — Examines mechanisms by which biofilms enhance bacterial resistance.
16: Colistin — Reviews colistin as a lastresort antibiotic against biofilmassociated infections.
17: Siderophore — Discusses bacterial iron acquisition strategies vital for biofilm growth.
18: Efflux pump — Analyzes bacterial defense mechanisms that expel antibiotics and enhance biofilm survival.
19: Biofilm prevention — Explores novel strategies for disrupting and preventing biofilms.
20: Prophage — Investigates the influence of bacteriophages on biofilm evolution.
21: Slime layer — Examines the protective slime layer that enhances bacterial adhesion.
Understanding biofilms is key to tackling antibiotic resistance, medical device infections, and industrial contamination. This book provides an essential foundation for anyone seeking to harness or combat biofilms in cuttingedge research. Whether you're an academic, professional, or hobbyist, this knowledge is invaluable.